Novel magnetic resonance imaging marker for tissue oxygenation and ischemic damage in stroke


  • Acceleration of longitudinal relaxation under hyperoxic challenge (hyperoxia-induced ÄR1), measured by a novel magnetic resonance imaging (MRI) method, correlates with tissue oxygenation and damage in a model of ischemic stroke (IS) and might be a more direct alternative to widely used blood oxygen-dependent MRI.

Why this matters

  • Blood oxygen-dependent MRI is limited by magnetic field vulnerability to various factors and difficulties calculating the partial pressure of tissue oxygen (PtO2).